Christopher K. Glass, MD, PhD

Dr. Glass is a founding member of the Department of Cellular and Molecular Medicine at the University of California, San Diego, where he is currently Professor of Cellular and Molecular Medicine and Professor of Medicine. Dr. Glass' laboratory investigates the role of nuclear receptors and other signal-dependent transcription factors in the regulation of macrophage development and function. His work is broadly relevant to the understanding of molecular mechanisms by which transcription factors control development and metabolism and how these factors may be exploited for the development of new drugs. Prior to his appointment as Professor, Dr. Glass was a postdoctoral fellow in Endocrinology and Metabolism at UCSD, following internships and residency training at Harvard Medical School's Brigham and Women's Hospital. He received a BS in Biophysics from the University of California, Berkeley, and MD and PhD degrees from UCSD.

John Katzenellenbogen, PhD
Founder

Dr. Katzenellenbogen is a Founder of Radius and is the Swanlund Professor of Chemistry at the University of Illinois at Urbana-Champaign. Dr. Katzenellenbogen's research is focused on aspects of the structure, function, and use of steroid receptors. He has prepared and evaluated receptor ligands having novel structures and activities and developed radiolabeled steroids for imaging receptor-positive tumors of the breast and prostate by positron emission tomography. More recently, Dr. Katzenellenbogen has initiated biochemical and biophysical studies on the dynamics of the estrogen receptors and their interaction with coregulator proteins. Dr. Katzenellenbogen is a Fellow of the American Academy of Arts and Sciences. He has given numerous named lecture presentations and received three NIH MERIT awards, the Paul C. Aebersold Award from the Society of Nuclear Medicine, and a Cope Scholar Award from the American Chemical Society. Dr. Katzenellenbogen conducted graduate studies with Professor E.J. Corey at Harvard University and received a PhD from Harvard University.

Stavros C. Manolagas, MD, PhD
Founder

Dr. Manolagas is a Founder of Radius and is Professor of Medicine and Director of the Division of Endocrinology and Metabolism, University of Arkansas for Medical Sciences (UAMS); Director of the UAMS/VA Center for Osteoporosis and Metabolic Bone Disease; and Chief of the Section of Endocrinology in the Central Arkansas Veterans Healthcare System. Dr. Manolagas's research interests include vitamin D metabolism; the interplay among hormones, cytokines, the hematopoietic/immune system and bone; cellular and molecular mechanisms of the pathogenesis of osteoporosis due to estrogen or androgen deficiency, old age, and glucocorticoid excess; mechanism of steroid hormone-receptor action; and the discovery of anabolic bone therapies. Previous positions include Professor of Medicine as well as Chief of the Section of Endocrinology and Metabolism in the Indianapolis VA Medical Center at Indiana University, and Associate Professor of Medicine in Residence at the University of California in San Diego. His honors and awards include the UAMS Dean's Distinguished Faculty Lecturer award, 2001; the inaugural Founders Award (Louis V. Avioli Award) of the American Society of Bone and Mineral Research, 2000; the 1999 AlliedSignal award for research on aging; and induction into the Association of American Physicians in 1996. Dr. Manolagas received an MD from the University of Athens Medical School and a PhD from the University of Manchester, England.

John T. Potts, MD, DSc
Founder

Dr. Potts is a Founder of Radius and is the Jackson Distinguished Professor of Clinical Medicine at the Massachusetts General Hospital (MGH) and Harvard Medical School. An internationally recognized authority on calcium metabolism and the hormonal mechanisms that govern it, Dr. Potts has been a pioneer in the chemistry and biology of parathyroid hormone (PTH) and its role in clinical disorders of bone and mineral ion metabolism. His research interests focus on calcium and bone metabolism and PTH; his clinical work is on disorders of calcium metabolism and osteoporosis. Previously, Dr. Potts served as Director of Research, as Chairman of the Department of Medicine and Physician-in-Chief, and as Chief of the Endocrine Unit at MGH. Previous to that, he conducted research on protein chemistry at the National Institutes of Health with Nobel laureate Christian Anfinsen. His honors and awards include the Association of Professors of Medicine's Robert H. Williams, MD, Distinguished Chair of Medicine Award (2002); the Biomedical Science Career Program Hope Award (2001); the Endocrine Society's Fred Konrad Koch Award (1991); and the American Society for Bone and Mineral Research's William F. Neumann Award (1987). He holds active and honorary memberships in a number of scientific and professional organizations including the Institute of Medicine and the American Academy of Arts and Sciences and is an elected member of the National Academy of Sciences. He received an MD from the University of Pennsylvania.