Publications

Transdermal Delivery of BA058, A Novel Analog of hPTHrP, with a Short Wear Time Microneedle Skin Patch in Post-Menopausal Women

G Hattersley, K Hansen, A Determan, K Brown, K Mckay, J Guerriero, D McCarthy, C R Lyttle, L St L O'Dea

Rapid Transdermal Delivery of BA058 by sMTS Microneedle Arrays; Pharmacokinetics in Rats and Monkeys, and Reversal of Bone Loss in Osteopenic Rats

G Hattersley, A Determan, K Hansen, C R Lyttle

BA058, a Novel Human PTHrP Analog, Restores Bone Mass in the Aged Osteopenic Ovariectomized Cynomolgus Monkey

N Doyle, A Varela, S Y Smith, G Hattersley

BA058, a Novel Human PTHrP Analog, Restores Bone Density at the Spine and Femur in Osteopenic Sprague-Dawley Rats within 13 Weeks

N Doyle, A Varela, S Y Smith, G Hattersley

Bone Anabolic Efficacy and Safety of BA058, A Novel Analog of hPTHrP: Results from a Phase 2 Clinical Trial in Postmenopausal Women with Osteoporosis

G Hattersley, J Bilezikian, J Guerriero, P Kumar, J Zanchetta, C R Lyttle, L St L O'Dea

BA058, a Novel hPTHrP Analog, Reverses Bone Loss and Improves Bone Strength in Ovariectomized Rats

G Hattersley, J Downall, M Shomali, K Gallacher and C R Lyttle.

A Selective Androgen Receptor Modulator (RAD140) Induces Inflammation In Rat Right Heart Ventricle – Evidence For An Androgen Specific, Species Specific Mechanism

C Miller, M Shomali, C R Lyttle, and G Hattersley

Development and Clinical/Preclinical Utilization of a BA058-sMTS Microneedle Drug Product targeting Osteoporosis

K Hansen, A Determan, K Brown, D Wirtanen, T Fenn, J Moseman, Y Zhang, D Dohmeier, G Hattersley

BA058, A Novel Analog of Human Parathyroid Hormone-related Protein: Early P1NP Elevation Precedes BMD Gains in Postmenopausal Women with Osteoporosis

G Hattersley, J Bilezikian, J Guerriero, P Kumar, J Zanchetta, C R Lyttle, L St L O'Dea

Rapid Transdermal Delivery of BA058 by sMTS Reverses Bone Loss in Osteopenic Rats

G Hattersley, J Downall, M Shomali, K Gallacher, A Determan, K Hansen and C R Lyttle

BA058, A Novel Analog of Human Parathyroid Hormone-related Protein, Exerts Significant Effects on BMD in Postmenopausal Women with Osteoporosis

G Hattersley, J Bilezikian, J Guerriero, P Kumar, J Zanchetta, C R Lyttle, L St L O'Dea

The Safety of BA058 in Postmenopausal Women with Osteoporosis: Results of a Phase 2 Clinical Trial

G Hattersley, J Bilezikian, J Guerriero, P Kumar, J Zanchetta, C. Lyttle, L St L O'Dea

Pharmacokinetics of Transdermal BA058 Administered by sMTS Microneedle Arrays in Rats and Monkeys

G Hattersley, A Determan, K Hansen and C R Lyttle

The Challenges of Selecting and Developing a New Route of Delivery for a Novel Osteoporosis Therapeutic

G Hattersley

A Novel Selective Estrogen Receptor Modulator (SERM), Demonstrates Evidence of Efficacy on Postmenopausal Hot Flashes in an Early Phase Human Study.

LStL O'Dea, D McCarthy, J Guerriero, C Miller, G Hattersley, C R Lyttle

A Novel Non-steroidal SARM with Anabolic Activity in Rats and Non-Human Primates

G Hattersley, M Shomali, K Gallacher, C R Lyttle, C Miller

A Novel SERM, has Efficacy in an Animal Model of Vasomotor Symptoms

G Hattersley, G Paquin, S Ho, I Merchenthaler, A Ogasawara, M Nakagawa, H Ogura and C Lyttle

A Novel Analog of Human Parathyroid Hormone-Related Peptide (PTHrP), Induced Evidence of Bone Formation without Evidence of Bone Resportion over 7-Days of Exposure.

L St L O'Dea, C R Lyttle, C Rosen